High Doses Of Celexa May Cause Heart Disorder: FDA

Law360, New York (August 24, 2011, 2:06 PM EDT) -- The U.S. Food and Drug Administration on Wednesday warned that high doses of Forest Laboratories Inc.'s antidepressant Celexa could cause a potentially fatal irregular heartbeat in users.

The regulator said it was revising the labels for Celexa and its generic versions to recommend that users not take more than 40 milligrams of the antidepressant daily. Previously, the citalopram drug label said certain patients may require a dose of 60 milligrams per day, according to the FDA.

"Studies did not show a benefit in the treatment of...
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